Question · asked by 1 review

Mutans streptococci detected in plaque or saliva at baseline vs No mutans streptococci detected in plaque or saliva at baseline: Development of any (cavitated or non-cavitated) carious lesion

Population
Children younger than 6 years with caries-free primary dentition (no cavitated or non-cavitated lesions at baseline)
Intervention
Mutans streptococci detected in plaque or saliva at baseline
Comparison
No mutans streptococci detected in plaque or saliva at baseline
Outcome
Development of any (cavitated or non-cavitated) carious lesion

Across the sample-based sensitivity analysis, mutans streptococci at baseline were associated with higher odds of developing caries.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Mutans streptococci detected in plaque or saliva at baseline vs No mutans streptococci detected in plaque or saliva at baseline
Development of carious lesions · Children younger than 6 years with caries-free primary dentition · 6 months to 3.5 years, Japan; Finland; USA; Sweden; Singapore, Overall sample sensitivity analysis
Across the sample-based sensitivity analysis, mutans streptococci at baseline were associated with higher odds of developing caries.
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and… (2023) All outcomes
OR 4.04 [3.33, 4.90]12 studies · 3313 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis.
2023 All outcomes
2022-11-1523Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.