Question · asked by 1 review

NSAIDs vs placebo: Adequate pain relief as reported by women

Population
women with perineal pain in the early postpartum period
Intervention
NSAIDs
Comparison
placebo
Outcome
Adequate pain relief as reported by women

NSAID may leads to higher adequate pain relief(4 hours after administration) compared with placebo (low certainty).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
NSAID vs placebo
Adequate pain relief(4 hours after administration) · women with perineal pain in the early postpartum period
NSAID may leads to higher adequate pain relief(4 hours after administration) compared with placebo (low certainty).
Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum period (2021) · Cochrane Headline outcomes only
RR 1.91 [1.64, 2.23]10 studies · 1573 participantsLow
NSAID vs placebo
Adequate pain relief(6 hours after administration) · women with perineal pain in the early postpartum period
It is very uncertain whether NSAID changes adequate pain relief(6 hours after administration) compared with placebo (very low certainty).
Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum period (2021) · Cochrane Headline outcomes only
RR 1.92 [1.69, 2.17]17 studies · 2079 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum period
2021 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.