Glucocorticosteroid avoidance or withdrawal vs glucocorticosteroid‐based immunosuppression: Infection
It is very uncertain whether glucocorticosteroid avoidance or withdrawal changes infection compared with glucocorticosteroid‐based immunosuppression (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Glucocorticosteroid avoidance or withdrawal vs glucocorticosteroid‐based immunosuppression Infection · liver transplanted patients It is very uncertain whether glucocorticosteroid avoidance or withdrawal changes infection compared with glucocorticosteroid‐based immunosuppression (very low certainty). Glucocorticosteroid‐free versus glucocorticosteroid‐containing immunosuppression for liver transplanted… (2018) · Cochrane Headline outcomes only | RR 0.88 [0.73, 1.05] | 8 studies · 778 participants | Very low |
Glucocorticosteroid avoidance or withdrawal vs glucocorticosteroid‐based immunosuppression Infection · liver transplanted patients Glucocorticosteroid avoidance or withdrawal showed no clear difference in infection compared with glucocorticosteroid‐based immunosuppression (low certainty). Glucocorticosteroid‐free versus glucocorticosteroid‐containing immunosuppression for liver transplanted… (2015) · Cochrane Headline outcomes onlyearlier version CD007606.PUB3, superseded | RR 0.88 [0.73, 1.05] | 8 studies · 778 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Glucocorticosteroid‐free versus glucocorticosteroid‐containing immunosuppression for liver transplanted patients 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.