Question · asked by 1 review

HAART + paclitaxel vs HAART + pegylated liposomal doxorubicin: Progression of Kaposi's sarcoma

Population
HIV‐infected adults with severe (T1) Kaposi's sarcoma
Intervention
HAART + paclitaxel
Comparison
HAART + pegylated liposomal doxorubicin
Outcome
Progression of Kaposi's sarcoma

HAART + paclitaxel showed no clear difference in progression of Kaposi's sarcoma compared with HAART + pegylated liposomal doxorubicin (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
HAART + paclitaxel vs HAART + pegylated liposomal doxorubicin
Progression of Kaposi's sarcoma · HIV‐infected adults with severe (T1) Kaposi's sarcoma
HAART + paclitaxel showed no clear difference in progression of Kaposi's sarcoma compared with HAART + pegylated liposomal doxorubicin (moderate certainty).
Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults (2014) · Cochrane Headline outcomes only
RR 1.04 [0.07, 15.73]1 study · 49 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults
2014 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.