Question · asked by 1 review

Complete cure and adverse events for terbinafine vs griseofulvin: Severe adverse events

Population
children with tinea capitis
Intervention
Complete cure and adverse events for terbinafine
Comparison
griseofulvin
Outcome
Severe adverse events

Complete cure and adverse events for terbinafine showed no clear difference in severe adverse events compared with griseofulvin (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Complete cure and adverse events for terbinafine vs griseofulvin
Severe adverse events · children with tinea capitis
Complete cure and adverse events for terbinafine showed no clear difference in severe adverse events compared with griseofulvin (moderate certainty).
Systemic antifungal therapy for tinea capitis in children (2016) · Cochrane Headline outcomes only
RR 0.97 [0.24, 3.88]1 study · 1549 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Systemic antifungal therapy for tinea capitis in children
2016 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.