Question · asked by 1 review

Single vs combination IV antibiotics: Time to next exacerbation

Population
adults and children with cystic fibrosis (during acute exacerbations of lung disease)
Intervention
Single
Comparison
combination IV antibiotics
Outcome
Time to next exacerbation

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Single vs combination IV antibiotics
Time to next exacerbation (weeks) · people with cystic fibrosis experiencing a pulmonary exacerbation
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (2015) · Cochrane Headline outcomes only
no estimate extracted1 study · 34 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis
2015 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.