High vs low stimulation: 50% or greater reduction in seizure frequency
High probably leads to higher 50% reduction in seizure frequency (responders) compared with low stimulation (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
High vs low stimulation 50% reduction in seizure frequency (responders) · patients with partial seizures High probably leads to higher 50% reduction in seizure frequency (responders) compared with low stimulation (moderate certainty). Vagus nerve stimulation for focal seizures (2015) · Cochrane Headline outcomes onlyearlier version CD002896.PUB2, superseded | RR 1.73 [1.13, 2.64] | 4 studies · 373 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Vagus nerve stimulation for focal seizures 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.