Liberal vs restrictive transfusion protocols: Infection
Liberal showed no clear difference in infection compared with restrictive transfusion protocols (high certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Liberal vs restrictive transfusion protocols Infection · adults and children (haemodynamically stable) with potential need for RBC transfusion Liberal showed no clear difference in infection compared with restrictive transfusion protocols (high certainty). Transfusion thresholds for guiding red blood cell transfusion (2021) · Cochrane Headline outcomes only | RR 0.97 [0.88, 1.07] | 25 studies · 17104 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Transfusion thresholds for guiding red blood cell transfusion 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.