Concomitant (concurrent) chemoradiotherapy vs Radiotherapy alone: Progression‐free survival (PSF)
Concomitant (concurrent) chemoradiotherapy led to lower progression-free survival, concomitant/alternating chemoradiotherapy… compared with radiotherapy alone (non-resectable tumours); GRADE not reported.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Concomitant (concurrent) chemoradiotherapy vs Radiotherapy alone (non-resectable tumours) Progression-free survival, concomitant/alternating chemoradiotherapy vs radiotherapy alone (pooled) · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer Concomitant (concurrent) chemoradiotherapy led to lower progression-free survival, concomitant/alternating chemoradiotherapy… compared with radiotherapy alone (non-resectable tumours); GRADE not reported. Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy (2011) · Cochrane All outcomesearlier version CD006386.PUB3, superseded | HR 0.77 [0.67, 0.89] | 6 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy 2021 · Cochrane All outcomes | 2021-09 | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.