Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment: Recurrent stroke of any type
Blood pressure‐lowering drugs (BPLDs) probably leads to lower recurrent stroke of any type compared with placebo or no treatment (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment Recurrent stroke of any type · patients with a history of TIA or stroke Blood pressure‐lowering drugs (BPLDs) probably leads to lower recurrent stroke of any type compared with placebo or no treatment (moderate certainty). Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in… (2018) · Cochrane Headline outcomes only | RR 0.81 [0.7, 0.93] | 8 studies · 35110 participants | Moderate |
Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment Time to recurrent stroke · patients with a history of TIA or stroke Blood pressure‐lowering drugs (BPLDs) showed no clear difference in time to recurrent stroke compared with placebo or no treatment (high certainty). Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in… (2018) · Cochrane Headline outcomes only | HR 0.82 [0.65, 1.03] | 3 studies · 26889 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients with a history of… 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.