Question · asked by 1 review

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage: Serious neonatal morbidity

Population
Not specified
Intervention
Cervical cerclage in combination with antibiotics and tocolytics
Comparison
cervical cerclage
Outcome
Serious neonatal morbidity

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes serious neonatal morbidity (Reported in Miller 2014 as 'composite… compared with cervical cerclage alone (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage alone
Serious neonatal morbidity (Reported in Miller 2014 as 'composite adverse outcome', which included the following neonatal morbidities: respiratory distress syndrome, necrotising enterocolitis, intraventricular haemorrhage, retinopathy of prematuri...
It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes serious neonatal morbidity (Reported in Miller 2014 as 'composite… compared with cervical cerclage alone (very low certainty).
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in… (2020) · Cochrane Headline outcomes only
RR 0.62 [0.31, 1.24]1 study · 50 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.