Question · asked by 1 review
Pregabalin vs placebo: Serious adverse events
- Population
- patients with chronic pancreatitis and pancreatic pain
- Intervention
- Pregabalin
- Comparison
- placebo
- Outcome
- Serious adverse events
Pregabalin showed no clear difference in serious adverse events compared with placebo (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Pregabalin vs placebo Serious adverse events · patients with chronic pancreatitis and pancreatic pain Pregabalin showed no clear difference in serious adverse events compared with placebo (low certainty). Pregabalin for decreasing pancreatic pain in chronic pancreatitis (2016) · Cochrane Headline outcomes only | RR 1.76 [0.35, 8.96] | 1 study · 64 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pregabalin for decreasing pancreatic pain in chronic pancreatitis 2016 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.