Early vs late AED withdrawal: Seizure relapse rate by time of withdrawal
Early may leads to higher seizure relapse rate by time of withdrawal compared with late AED withdrawal (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Early vs late AED withdrawal Seizure relapse rate by time of withdrawal · individuals with epilepsy in remission Early may leads to higher seizure relapse rate by time of withdrawal compared with late AED withdrawal (low certainty). Early versus late antiepileptic drug withdrawal for people with epilepsy in remission (2015) · Cochrane Headline outcomes only | RR 1.34 [1.13, 1.59] | 5 studies · 924 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Early versus late antiepileptic drug withdrawal for people with epilepsy in remission 2015 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.