Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D): Dental caries in children
- Population
- Children aged 4 to 6 years whose mothers' prenatal vitamin D status was assessed
- Intervention
- Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy)
- Comparison
- Adequate prenatal vitamin D (sufficient maternal 25(OH)D)
- Outcome
- Dental caries in children
Among children aged 4-6 years, prenatal vitamin D deficiency is associated with significantly higher odds of dental caries (OR 1.44, 95% CI 1.32-1.56); ungraded.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D) Dental caries in children · Children aged 4 to 6 years whose mothers' prenatal vitamin D status was assessed · Prenatal exposure; dental caries at 4 to 6 years, Observational pregnancy/birth-cohort studies (one cross-sectional), mostly in developed countries (USA, Canada, Japan, Australia, Spain, Netherlands, Poland, New Zealand, Turkey), Children's age subgroup: 4 to 6 years Among children aged 4-6 years, prenatal vitamin D deficiency is associated with significantly higher odds of dental caries (OR 1.44, 95% CI 1.32-1.56); ungraded. Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) All outcomes | OR 1.44 [1.32, 1.56] | 8 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic review and meta-analysis. 2024 All outcomes | 5 October 2023 (search range 2000 to October 2023) | 16 | Not applicable |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D) · Infants and children (aged about 2 to 8 years) whose mothers' vitamin D status was… · 1 review
- Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D) · Children aged 6 to 8 years whose mothers' prenatal vitamin D status was assessed · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.