Question · asked by 1 review

Adjunctive steroid vs placebo: Hearing loss

Adjunctive steroid showed no clear difference in hearing loss at 2 years of age compared with placebo (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Adjunctive steroid vs placebo
Hearing loss at 2 years of age · neonates with clinical and microbiological features of bacterial meningitis
Adjunctive steroid showed no clear difference in hearing loss at 2 years of age compared with placebo (low certainty).
Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis (2015) · Cochrane Headline outcomes only
RR 1.8 [0.18, 18.21]1 study · 38 participantsLow
Adjunctive steroid vs placebo
Hearing loss at 4 to 10 weeks after discharge · neonates with clinical and microbiological features of bacterial meningitis
Adjunctive steroid may leads to lower hearing loss at 4 to 10 weeks after discharge compared with placebo (low certainty).
Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis (2015) · Cochrane Headline outcomes only
RR 0.41 [0.17, 0.98]1 study · 59 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.