Question · asked by 1 review
Corticosteroids vs control: Improvement in disability grade after 4 weeks
Corticosteroid showed no clear difference in improvement by ≥ 1 grades after 4 weeks GBS disability grade scale compared with control (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Corticosteroid vs control Disability grade change after 4 weeks GBS disability grade. Scale from: 0 to 6 · people with Guillain‐Barré syndrome Corticosteroids for Guillain‐Barré syndrome (2016) · Cochrane Headline outcomes only | no estimate extracted | 6 studies · 587 participants | Moderate |
Corticosteroid vs control Disability grade change after 4 weeks ‐ oral regimens GBS disability grade. Scale from: 0 to 6 · people with Guillain‐Barré syndrome Corticosteroids for Guillain‐Barré syndrome (2016) · Cochrane Headline outcomes only | no estimate extracted | 4 studies · 120 participants | Very low |
Corticosteroid vs control Disability grade change after 4 weeks ‐ intravenous regimens GBS disability grade. Scale from: 0 to 6 · people with Guillain‐Barré syndrome Corticosteroids for Guillain‐Barré syndrome (2016) · Cochrane Headline outcomes only | no estimate extracted | 2 studies · 467 participants | Moderate |
Corticosteroid vs control Improvement by ≥ 1 grades after 4 weeks GBS disability grade scale · people with Guillain‐Barré syndrome Corticosteroid showed no clear difference in improvement by ≥ 1 grades after 4 weeks GBS disability grade scale compared with control (moderate certainty). Corticosteroids for Guillain‐Barré syndrome (2016) · Cochrane Headline outcomes only | RR 1.08 [0.93, 1.24] | 5 studies · 567 participants | Moderate |
Corticosteroid vs control Disability grade change after four weeks GBS disability grade. Scale from: 0 to 6. · patients with Guillain‐Barré syndrome Corticosteroids for Guillain‐Barré syndrome (2012) · Cochrane Headline outcomes onlyearlier version CD001446.PUB4, superseded | no estimate extracted | 6 studies · 587 participants | Moderate |
Corticosteroid vs control Disability grade change after four weeks ‐ oral regimens GBS disability grade. Scale from: 0 to 6. · patients with Guillain‐Barré syndrome Corticosteroids for Guillain‐Barré syndrome (2012) · Cochrane Headline outcomes onlyearlier version CD001446.PUB4, superseded | no estimate extracted | 4 studies · 120 participants | Very low |
Corticosteroid vs control Disability grade change after four weeks ‐ intravenous regimens GBS disability grade. Scale from: 0 to 6. · patients with Guillain‐Barré syndrome Corticosteroids for Guillain‐Barré syndrome (2012) · Cochrane Headline outcomes onlyearlier version CD001446.PUB4, superseded | no estimate extracted | 2 studies · 467 participants | Moderate |
Corticosteroid vs control Disability grade change after four weeks GBS disability grade. Scale from: 0 to 6. · patients with Guillain‐Barré syndrome Corticosteroids for Guillain‐Barré syndrome (2010) · Cochrane Headline outcomes onlyearlier version CD001446.PUB3, superseded | no estimate extracted | 6 studies · 587 participants | Moderate |
Corticosteroid vs control Disability grade change after four weeks ‐ oral regimens GBS disability grade. Scale from: 0 to 6. · patients with Guillain‐Barré syndrome Corticosteroids for Guillain‐Barré syndrome (2010) · Cochrane Headline outcomes onlyearlier version CD001446.PUB3, superseded | no estimate extracted | 4 studies · 120 participants | Very low |
Corticosteroid vs control Disability grade change after four weeks ‐ intravenous regimens GBS disability grade. Scale from: 0 to 6. · patients with Guillain‐Barré syndrome Corticosteroids for Guillain‐Barré syndrome (2010) · Cochrane Headline outcomes onlyearlier version CD001446.PUB3, superseded | no estimate extracted | 2 studies · 467 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Corticosteroids for Guillain‐Barré syndrome 2016 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.