30% SDF solution (applied annually) vs Fluoride varnish: Arrest of advanced cavitated carious lesions on any coronal surface
- Population
- Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth)
- Intervention
- 30% SDF solution (applied annually)
- Comparison
- Fluoride varnish
- Outcome
- Arrest of advanced cavitated carious lesions on any coronal surface
30% SDF solution (applied annually) was more effective than 5% NaF varnish (once weekly for 3 weeks) for arrest or reversal of cavitated coronal carious lesions (RR 1.41, 95% CI 1.2 to 1.66; high certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
30% SDF solution (applied annually) vs 5% NaF varnish (once weekly for 3 weeks) Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 30 mo, Dental practice (professionally applied or prescribed nonrestorative caries treatments; parallel and split-mouth RCTs) 30% SDF solution (applied annually) was more effective than 5% NaF varnish (once weekly for 3 weeks) for arrest or reversal of cavitated coronal carious lesions (RR 1.41, 95% CI 1.2 to 1.66; high certainty). Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) All outcomes | RR 1.41 [1.2, 1.66] | 1 study · 309 participants | High |
30% SDF solution (applied annually) vs 5% NaF varnish (once weekly for 3 weeks) Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 18 mo, Dental practice (professionally applied or prescribed nonrestorative caries treatments; parallel and split-mouth RCTs) 30% SDF solution (applied annually) was more effective than 5% NaF varnish (once weekly for 3 weeks) for arrest or reversal of cavitated coronal carious lesions (RR 1.47, 95% CI 1.22 to 1.76; high certainty). Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) All outcomes | RR 1.47 [1.22, 1.76] | 1 study · 309 participants | High |
30% SDF solution (applied annually) vs 5% NaF varnish (once weekly for 3 weeks) Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 12 mo, Dental practice (professionally applied or prescribed nonrestorative caries treatments; parallel and split-mouth RCTs) 30% SDF solution (applied annually) was more effective than 5% NaF varnish (once weekly for 3 weeks) for arrest or reversal of cavitated coronal carious lesions (RR 1.48, 95% CI 1.11 to 1.97; high certainty). Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) All outcomes | RR 1.48 [1.11, 1.97] | 1 study · 309 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. 2019 All outcomes | June 2017 | 54 | Critically Low / Critically Low |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- 30% SDF solution (applied annually) vs 30% SDF solution (once weekly for 3 weeks) · Preschool children with advanced cavitated carious lesions on any coronal surface… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.