Question · asked by 1 review

Topical quinolone vs boric acid: Resolution of ear discharge (1 to 2 weeks) Quinolones

Population
chronic suppurative otitis media
Intervention
Topical quinolone
Comparison
boric acid
Outcome
Resolution of ear discharge (1 to 2 weeks) Quinolones

Topical antibiotics (quinolones) probably leads to higher resolution of ear discharge (1 to 2 weeks) Quinolones compared with boric acid (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Topical antibiotics (quinolones) vs boric acid
Resolution of ear discharge (1 to 2 weeks) Quinolones · chronic suppurative otitis media
Topical antibiotics (quinolones) probably leads to higher resolution of ear discharge (1 to 2 weeks) Quinolones compared with boric acid (moderate certainty).
Antibiotics versus topical antiseptics for chronic suppurative otitis media (2020) · Cochrane Headline outcomes only
RR 1.86 [1.48, 2.35]1 study · 411 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antibiotics versus topical antiseptics for chronic suppurative otitis media
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.