Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment: Early onset GBS disease (sepsis and/or meningitis within the first seven days of life))
It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes early onset GBS disease (sepsis and/or meningitis within the first… compared with placebo or no treatment (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment Early onset GBS disease (sepsis and/or meningitis within the first seven days of life)) · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes early onset GBS disease (sepsis and/or meningitis within the first… compared with placebo or no treatment (very low certainty). Vaginal chlorhexidine during labour to prevent early‐onset neonatal group B streptococcal infection (2014) · Cochrane Headline outcomes only | RR 2.32 [0.34, 15.63] | 2 studies · 987 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Vaginal chlorhexidine during labour to prevent early‐onset neonatal group B streptococcal infection 2014 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.