Question · asked by 1 review

Clotrimazole (partially absorbed from GI tract) vs placebo: Episodes of confirmed vaginal candidiasis fungal smear

Clotrimazole showed no clear difference in episode of confirmed vaginal candidiasis fungal smear compared with placebo (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Clotrimazole vs Placebo
Episode of confirmed vaginal candidiasis fungal smear · patients with prevention and treatment of vulvovaginal candidiasis in women with HIV infection
Clotrimazole showed no clear difference in episode of confirmed vaginal candidiasis fungal smear compared with placebo (low certainty).
Interventions for prevention and treatment of vulvovaginal candidiasis in women with HIV infection (2011) · Cochrane Headline outcomes only
RR 0.49 [0.22, 1.09]1 study · 106 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for prevention and treatment of vulvovaginal candidiasis in women with HIV infection
2011 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.