Question · asked by 1 review

Dexamethasone vs control: Postoperative wound or systemic infection

Dexamethasone showed no clear difference in postoperative wound or systemic infection compared with control (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Dexamethasone vs control
Postoperative wound or systemic infection · surgical patients undergoing various types of surgery (e.g. abdominal, brain, cardiac, and orthopaedic surgery)
Dexamethasone showed no clear difference in postoperative wound or systemic infection compared with control (moderate certainty).
Adverse side effects of dexamethasone in surgical patients (2018) · Cochrane Headline outcomes onlyearlier version CD011940.PUB2, superseded
OR 1.01 [0.8, 1.27]27 studies · 4931 participantsModerate
Dexamethasone vs control
Postoperative wound or systemic infection · surgical patients undergoing various types of surgery (e.g. abdominal, brain, cardiac, and orthopaedic surgery)
Dexamethasone showed no clear difference in postoperative wound or systemic infection compared with control (moderate certainty).
Adverse side effects of dexamethasone in surgical patients (2018) · Cochrane Headline outcomes only
OR 1.01 [0.8, 1.27]26 studies · 4603 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Adverse side effects of dexamethasone in surgical patients
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.