Question · asked by 1 review

Antihelminthics vs control: Gestational age (preterm birth < 37 weeks)

Population
pregnant women in second trimester of pregnancy
Intervention
Antihelminthics
Comparison
control
Outcome
Gestational age (preterm birth < 37 weeks)

Antihelminthics showed no clear difference in preterm birth (birth before 37 weeks of gestation) compared with control (low certainty).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%
FindingEffectStudiesGRADE certainty
Antihelminthics vs control
Preterm birth (birth before 37 weeks of gestation) · pregnant women in second trimester of pregnancy
Antihelminthics showed no clear difference in preterm birth (birth before 37 weeks of gestation) compared with control (low certainty).
Effect of mass deworming with antihelminthics for soil‐transmitted helminths during pregnancy (2021) · Cochrane Headline outcomes only
RR 0.84 [0.38, 1.86]1 study · 1042 participantsLow
Antihelminthics vs control
Preterm birth (birth before 37 weeks of gestation) · pregnant women in second trimester of pregnancy
Antihelminthics showed no clear difference in preterm birth (birth before 37 weeks of gestation) compared with control (moderate certainty).
Effect of mass deworming with antihelminthics for soil‐transmitted helminths during pregnancy (2015) · Cochrane Headline outcomes onlyearlier version CD005547.PUB3, superseded
RR 0.88 [0.43, 1.78]2 studies · 1318 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Effect of mass deworming with antihelminthics for soil‐transmitted helminths during pregnancy
2021 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.