Cochrane · systematic review · CD005547
Effect of mass deworming with antihelminthics for soil‐transmitted helminths during pregnancy
Salam, RA, Das, JK, Bhutta, ZA · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyAntihelminthics versus control for soil‐transmitted helminths during pregnancy
Population: pregnant women in second trimester of pregnancy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Maternal anaemia in third trimester (< 11 g/dL) Antihelminthics vs control | RR 0.85 [0.72, 1] | 5 studies · 5745 participants | Low Downgraded: risk of bias, inconsistency |
Preterm birth (birth before 37 weeks of gestation) Antihelminthics vs control | RR 0.84 [0.38, 1.86] | 1 study · 1042 participants | Low Downgraded: imprecision |
Perinatal mortality Antihelminthics vs control | RR 1.01 [0.67, 1.52] | 3 studies · 3356 participants | Low Downgraded: imprecision, indirectness |
Antihelminthics versus control for soil‐transmitted helminths during pregnancy
Population: pregnant women in second trimester of pregnancy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Maternal anaemia in third trimester (< 11 g/dL) ‐ all study groups Antihelminthics vs control | RR 0.94 [0.81, 1.1] | 4 studies · 3266 participants | Low Downgraded: risk of bias |
Low birthweight Antihelminthics vs control | RR 1 [0.79, 1.27] | 3 studies · 3255 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Preterm birth (birth before 37 weeks of gestation) Antihelminthics vs control | RR 0.88 [0.43, 1.78] | 2 studies · 1318 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Perinatal mortality Antihelminthics vs control | RR 1.09 [0.71, 1.67] | 2 studies · 3385 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |