Surgery plus radiotherapy vs Radiotherapy alone: Total mortality
- Population
- Adults with oral cavity or oropharyngeal cancer
- Intervention
- Surgery plus radiotherapy
- Comparison
- Radiotherapy alone
- Outcome
- Total mortality
It is very uncertain whether surgery plus radiotherapy changes total mortality compared with radiotherapy alone (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Surgery plus radiotherapy vs Radiotherapy alone Total mortality · Adults with oral cavity or oropharyngeal cancer · 3 years It is very uncertain whether surgery plus radiotherapy changes total mortality compared with radiotherapy alone (very low certainty). Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment (2023) · Cochrane All outcomes | HR 0.24 [0.10, 0.59] | 1 study · 35 participants | Very low |
Surgery plus radiotherapy vs Radiotherapy alone Total mortality · Adults with oral cavity or oropharyngeal cancer · 3 years It is very uncertain whether surgery plus radiotherapy changes total mortality compared with radiotherapy alone (very low certainty). Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment (2018) · Cochrane All outcomesearlier version CD006205.PUB4, superseded | HR 0.24 [0.10, 0.59] | 1 study · 35 participants | Very low |
Surgery plus radiotherapy vs Radiotherapy alone Total mortality · Adults with oral cavity or oropharyngeal cancer · 23 months (interim) Surgery plus radiotherapy led to lower total mortality compared with radiotherapy alone; GRADE not reported. Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment (2011) · Cochrane All outcomesearlier version CD006205.PUB3, superseded | HR 0.24 [0.10, 0.59] | 1 study · 35 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes | 2022-02 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy) · Adults with oral cavity or oropharyngeal cancer · 1 review
- Surgery plus radiotherapy vs surgery · People with squamous cell carcinoma of the oral cavity or oropharynx · 0 reviews
- Surgery plus radiotherapy vs Radiotherapy alone · People with squamous cell carcinoma of the oral cavity or oropharynx · 0 reviews
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.