Question · asked by 1 review

Beta‐blockers vs placebo or no intervention: Myocardial infarction

Beta‐blockers showed no clear difference in myocardial infarction at maximum compared with placebo or no intervention (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Beta‐blockers vs placebo or no intervention
Myocardial infarction at maximum · patients with suspected or diagnosed myocardial infarction
Beta‐blockers showed no clear difference in myocardial infarction at maximum compared with placebo or no intervention (low certainty).
Beta‐blockers for suspected or diagnosed acute myocardial infarction (2019) · Cochrane Headline outcomes only
RR 0.89 [0.75, 1.08]14 studies · 6825 participantsLow
Beta‐blockers vs placebo or no intervention
Myocardial infarction at 'less than 3 months' · patients with suspected or diagnosed myocardial infarction
Beta‐blockers probably leads to lower myocardial infarction at 'less than 3 months' compared with placebo or no intervention (moderate certainty).
Beta‐blockers for suspected or diagnosed acute myocardial infarction (2019) · Cochrane Headline outcomes only
RR 0.82 [0.74, 0.9]18 studies · 67562 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Beta‐blockers for suspected or diagnosed acute myocardial infarction
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.