Question · asked by 1 review

NSAIDs vs placebo: Maternal drug adverse effects (6 hours after administration)

Population
women with perineal pain in the early postpartum period
Intervention
NSAIDs
Comparison
placebo
Outcome
Maternal drug adverse effects (6 hours after administration)

NSAID showed no clear difference in maternal drug adverse effects(6 hours after administration) compared with placebo (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
NSAID vs placebo
Maternal drug adverse effects(6 hours after administration) · women with perineal pain in the early postpartum period
NSAID showed no clear difference in maternal drug adverse effects(6 hours after administration) compared with placebo (low certainty).
Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum period (2021) · Cochrane Headline outcomes only
RR 1.38 [0.71, 2.7]13 studies · 1388 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum period
2021 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.