Question · asked by 1 review

Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment: Death by any cause

Blood pressure‐lowering drugs (BPLDs) showed no clear difference in death by any cause compared with placebo or no treatment (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment
Death by any cause · patients with a history of TIA or stroke
Blood pressure‐lowering drugs (BPLDs) showed no clear difference in death by any cause compared with placebo or no treatment (moderate certainty).
Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in… (2018) · Cochrane Headline outcomes only
RR 0.98 [0.91, 1.05]8 studies · 35110 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Blood pressure‐lowering treatment for preventing recurrent stroke, major vascular events, and dementia in patients with a history of…
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.