Question · asked by 1 review

Bleomycin vs ABV: Primary outcome: partial clinical response

Population
HIV‐infected adults with severe (T1) Kaposi's sarcoma
Intervention
Bleomycin
Comparison
ABV
Outcome
Primary outcome: partial clinical response

It is very uncertain whether bleomycin changes clinical response ‐ partial response compared with ABV (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Bleomycin vs ABV
Clinical response ‐ partial response · HIV‐infected adults with severe (T1) Kaposi's sarcoma
It is very uncertain whether bleomycin changes clinical response ‐ partial response compared with ABV (very low certainty).
Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults (2014) · Cochrane Headline outcomes only
RR 0.11 [0.01, 1.86]1 study · 24 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults
2014 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.