Question · asked by 1 review

Nitrofurantoin and close surveillance vs close surveillance alone: Preterm birth

Population
pregnant women with a history of one or more UTI before or during pregnancy
Intervention
Nitrofurantoin and close surveillance
Comparison
close surveillance alone
Outcome
Preterm birth

It is very uncertain whether nitrofurantoin and close surveillance changes preterm birth (< 37 weeks) compared with close surveillance alone (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Nitrofurantoin and close surveillance vs close surveillance alone
Preterm birth (< 37 weeks) · pregnant women with a history of one or more UTI before or during pregnancy
It is very uncertain whether nitrofurantoin and close surveillance changes preterm birth (< 37 weeks) compared with close surveillance alone (very low certainty).
Interventions for preventing recurrent urinary tract infection during pregnancy (2015) · Cochrane Headline outcomes only
RR 1.18 [0.42, 3.35]1 study · 147 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for preventing recurrent urinary tract infection during pregnancy
2015 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.