Mefloquine plus cotrimoxazole vs cotrimoxazole: Placental malaria
Mefloquine plus cotrimoxazole leads to lower placental malaria (PCR) compared with cotrimoxazole (high certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Mefloquine plus cotrimoxazole vs cotrimoxazole Placental malaria (PCR) · HIV‐infected pregnant women Mefloquine plus cotrimoxazole leads to lower placental malaria (PCR) compared with cotrimoxazole (high certainty). Mefloquine for preventing malaria in pregnant women (2018) · Cochrane Headline outcomes onlyearlier version CD011444.PUB2, superseded | RR 0.28 [0.14, 0.57] | 2 studies · 977 participants | High |
Mefloquine plus cotrimoxazole vs cotrimoxazole Placental malaria (PCR) · HIV‐infected pregnant women Mefloquine plus cotrimoxazole probably leads to lower placental malaria (PCR) compared with cotrimoxazole (moderate certainty). Mefloquine for preventing malaria in pregnant women (2018) · Cochrane Headline outcomes only | RR 0.28 [0.14, 0.57] | 2 studies · 977 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Mefloquine for preventing malaria in pregnant women 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.