Question · asked by 1 review

RISPERIDONE vs QUETIAPINE: Adverse effects ‐ movement disorders

Population
psychosis‐induced aggression or agitation (rapid tranquillisation)
Intervention
RISPERIDONE
Comparison
QUETIAPINE
Outcome
Adverse effects ‐ movement disorders

It is very uncertain whether RISPERIDONE changes adverse effects: movement disorders over 24 hours compared with OTHER ANTIPSYCHOTIC: c. QUETIAPINE (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
RISPERIDONE vs OTHER ANTIPSYCHOTIC: c. QUETIAPINE
Adverse effects: movement disorders over 24 hours · psychosis‐induced aggression or agitation (rapid tranquillisation)
It is very uncertain whether RISPERIDONE changes adverse effects: movement disorders over 24 hours compared with OTHER ANTIPSYCHOTIC: c. QUETIAPINE (very low certainty).
Risperidone for psychosis‐induced aggression or agitation (rapid tranquillisation) (2018) · Cochrane Headline outcomes only
RR 1.67 [0.46, 6.06]1 study · 40 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Risperidone for psychosis‐induced aggression or agitation (rapid tranquillisation)
2018 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.