Question · asked by 1 review
Radioisotopes vs placebo: Pain flares
- Population
- patients with metastatic bone pain
- Intervention
- Radioisotopes
- Comparison
- placebo
- Outcome
- Pain flares
Radioisotopes showed no clear difference in pain flares compared with placebo (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Radioisotopes vs Placebo Pain flares · patients with metastatic bone pain Radioisotopes showed no clear difference in pain flares compared with placebo (low certainty). Radioisotopes for metastatic bone pain (2011) · Cochrane Headline outcomes only | RR 0.74 [0.27, 2.06] | 2 studies · 270 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Radioisotopes for metastatic bone pain 2011 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.