Question · asked by 1 review

Tranexamic acid vs placebo (saline solution or sterile water): Surgical field bleeding score (during surgery or < 30 minutes after surgery)

Population
adults and children with chronic rhinosinusitis with or without nasal polyps
Intervention
Tranexamic acid
Comparison
placebo (saline solution or sterile water)
Outcome
Surgical field bleeding score (during surgery or < 30 minutes after surgery)

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Tranexamic acid vs placebo (saline solution or sterile water)
Surgical field bleeding score (during surgery or < 30 minutes after surgery) · adults and children with chronic rhinosinusitis with or without nasal polyps
Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery (2023) · Cochrane Headline outcomes only
no estimate extracted13 studies · 772 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery
2023 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.