Question · asked by 1 review
Antihypertensive drug therapy vs control: Cardiovascular mortality and morbidity Mean duration of 3.7 years
- Population
- adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)
- Intervention
- Antihypertensive drug therapy
- Comparison
- control
- Outcome
- Cardiovascular mortality and morbidity Mean duration of 3.7 years
Antihypertensive drug therapy may leads to lower total cardiovascular mortality + morbidity compared with control (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antihypertensive drug therapy vs control Total cardiovascular mortality + morbidity · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension) Antihypertensive drug therapy may leads to lower total cardiovascular mortality + morbidity compared with control (low certainty). Pharmacotherapy for hypertension in adults aged 18 to 59 years (2017) · Cochrane Headline outcomes only | RR 0.78 [0.67, 0.91] | 6 studies · 17278 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacotherapy for hypertension in adults aged 18 to 59 years 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.