Question · asked by 1 review
Antibiotics vs placebo or no antibiotic: Perinatal mortality
- Population
- pregnant women with prelabour rupture of membranes at or near term
- Intervention
- Antibiotics
- Comparison
- placebo or no antibiotic
- Outcome
- Perinatal mortality
Any antibiotic showed no clear difference in perinatal mortality compared with placebo or no antibiotic (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Any antibiotic vs placebo or no antibiotic Perinatal mortality · pregnant women with prelabour rupture of membranes at or near term Any antibiotic showed no clear difference in perinatal mortality compared with placebo or no antibiotic (low certainty). Antibiotics for prelabour rupture of membranes at or near term (2014) · Cochrane Headline outcomes only | RR 1.98 [0.6, 6.55] | 4 studies · 2639 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antibiotics for prelabour rupture of membranes at or near term 2014 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.