Question · asked by 1 review
CHLORPROMAZINE vs metiapine: Global State: clinically important improvement
- Population
- patients with schizophrenia
- Intervention
- CHLORPROMAZINE
- Comparison
- metiapine
- Outcome
- Global State: clinically important improvement
It is very uncertain whether chlorpromazine changes global state: clinically important improvement Clinical Global… compared with metiapine (very low certainty).
What each review found
Current versions onlyNo studies found 1 · 50%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chlorpromazine vs metiapine Global state: clinically important improvement Clinical Global Impression · people with schizophrenia It is very uncertain whether chlorpromazine changes global state: clinically important improvement Clinical Global… compared with metiapine (very low certainty). Chlorpromazine versus metiapine for schizophrenia (2017) · Cochrane Headline outcomes only | RR 1.11 [0.84, 1.47] | 2 studies · 120 participants | Very low |
Chlorpromazine vs metiapine Mental state: clinically important improvement · people with schizophrenia The review found no eligible studies for this question. Chlorpromazine versus metiapine for schizophrenia (2017) · Cochrane Headline outcomes only | no estimate extracted | Not reported | No studies found |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Chlorpromazine versus metiapine for schizophrenia 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.