Question · asked by 1 review

CHLORPROMAZINE vs metiapine: Global State: clinically important improvement

Population
patients with schizophrenia
Intervention
CHLORPROMAZINE
Comparison
metiapine
Outcome
Global State: clinically important improvement

It is very uncertain whether chlorpromazine changes global state: clinically important improvement Clinical Global… compared with metiapine (very low certainty).

What each review found

Include earlier review versions
No studies found 1 · 50%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Chlorpromazine vs metiapine
Global state: clinically important improvement Clinical Global Impression · people with schizophrenia
It is very uncertain whether chlorpromazine changes global state: clinically important improvement Clinical Global… compared with metiapine (very low certainty).
Chlorpromazine versus metiapine for schizophrenia (2017) · Cochrane Headline outcomes only
RR 1.11 [0.84, 1.47]2 studies · 120 participantsVery low
Chlorpromazine vs metiapine
Mental state: clinically important improvement · people with schizophrenia
The review found no eligible studies for this question.
Chlorpromazine versus metiapine for schizophrenia (2017) · Cochrane Headline outcomes only
no estimate extractedNot reportedNo studies found

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Chlorpromazine versus metiapine for schizophrenia
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.