Question · asked by 1 review
Mirtazapine vs placebo: Participant‐reported pain relief of 50% or greater
- Population
- adults with fibromyalgia
- Intervention
- Mirtazapine
- Comparison
- placebo
- Outcome
- Participant‐reported pain relief of 50% or greater
Mirtazapine showed no clear difference in participant‐reported pain relief of 50% or greater (substantial… compared with placebo (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Mirtazapine vs placebo Participant‐reported pain relief of 50% or greater (substantial improvement) · adult participants with fibromyalgia Mirtazapine showed no clear difference in participant‐reported pain relief of 50% or greater (substantial… compared with placebo (low certainty). Mirtazapine for fibromyalgia in adults (2018) · Cochrane Headline outcomes only | RD 0.05 | 3 studies · 591 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Mirtazapine for fibromyalgia in adults 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.