Mid‐dose mifepristone (25 mg‐50 mg) vs levonorgestrel 1.5 mg: Specific side effects ‐ spotting/bleeding after treatment
Mid‐dose mifepristone (25 mg‐50 mg) may leads to lower specific side effect ‐ spotting/bleeding after treatment compared with levonorgestrel 1.5 mg (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Mid‐dose mifepristone (25 mg‐50 mg) vs levonorgestrel 1.5 mg Specific side effect ‐ spotting/bleeding after treatment · women seeking emergency contraception Mid‐dose mifepristone (25 mg‐50 mg) may leads to lower specific side effect ‐ spotting/bleeding after treatment compared with levonorgestrel 1.5 mg (low certainty). Interventions for emergency contraception (2019) · Cochrane Headline outcomes only | RR 0.61 [0.42, 0.88] | 9 studies · 1796 participants | Low |
Mid‐dose mifepristone (25 mg‐50 mg) vs levonorgestrel 1.5 mg Specific side effect ‐ spotting/bleeding after treatment · women seeking emergency contraception Mid‐dose mifepristone (25 mg‐50 mg) may leads to lower specific side effect ‐ spotting/bleeding after treatment compared with levonorgestrel 1.5 mg (low certainty). Interventions for emergency contraception (2017) · Cochrane Headline outcomes onlyearlier version CD001324.PUB5, superseded | RR 0.61 [0.42, 0.88] | 9 studies · 1796 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for emergency contraception 2019 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.