Any antibiotic regimen plus N‐acetylcysteine vs the same regimen without N‐acetylcysteine (with or without placebo): Eradication rate
It is very uncertain whether any antibiotic regimen plus N‐acetylcysteine changes eradication rate compared with the same regimen without N‐acetylcysteine (with or without placebo) (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Any antibiotic regimen plus N‐acetylcysteine vs the same regimen without N‐acetylcysteine (with or without placebo) Eradication rate · people withH pylori infection It is very uncertain whether any antibiotic regimen plus N‐acetylcysteine changes eradication rate compared with the same regimen without N‐acetylcysteine (with or without placebo) (very low certainty). N‐acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication (2019) · Cochrane Headline outcomes only | RR 0.74 [0.51, 1.08] | 8 studies · 559 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| N‐acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication 2019 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.