Question · asked by 1 review

Dihydropyridine calcium channel blockers vs placebo: Variation in the decrease in 24‐hour ambulatory hourly DBP (at 3 to 12 weeks)

Population
adults with primary hypertension
Intervention
Dihydropyridine calcium channel blockers
Comparison
placebo
Outcome
Variation in the decrease in 24‐hour ambulatory hourly DBP (at 3 to 12 weeks)

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Dihydropyridine calcium channel blockers vs placebo
Variation in the decrease in 24‐hour ambulatory hourly diastolic blood pressure at 3‐12 weeks · adults with primary hypertension
Time course for blood pressure lowering of dihydropyridine calcium channel blockers (2014) · Cochrane Headline outcomes only
no estimate extracted16 studies · 2768 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Time course for blood pressure lowering of dihydropyridine calcium channel blockers
2014 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.