Allopurinol mouthrinse vs placebo/no treatment: Oral mucositis (any severity)
Allopurinol mouthrinse showed no clear difference in oral mucositis (any severity) compared with placebo/no treatment; GRADE not reported.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Allopurinol mouthrinse vs Placebo/no treatment Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies · Median 28 days Allopurinol mouthrinse showed no clear difference in oral mucositis (any severity) compared with placebo/no treatment; GRADE not reported. Interventions for preventing oral mucositis for patients with cancer receiving treatment (2011) · Cochrane All outcomes | RR 0.77 [0.5, 1.19] | 4 studies | GRADE not reported |
Allopurinol mouthrinse vs Placebo/no treatment Oral mucositis (any severity) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies · Median 28 days Allopurinol mouthrinse showed no clear difference in oral mucositis (any severity) compared with placebo/no treatment; GRADE not reported. Interventions for preventing oral mucositis for patients with cancer receiving treatment (2010) · Cochrane All outcomesearlier version CD000978.PUB4, superseded | RR 0.77 [0.5, 1.19] | 4 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for preventing oral mucositis for patients with cancer receiving treatment 2011 · Cochrane All outcomes | 2011-02 | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.