Topical quinolone vs boric acid: Ear pain (otalgia) or discomfort or local irritation
- Population
- chronic suppurative otitis media
- Intervention
- Topical quinolone
- Comparison
- boric acid
- Outcome
- Ear pain (otalgia) or discomfort or local irritation
Topical antibiotics (quinolones) may leads to lower ear pain, discomfort, irritation compared with boric acid (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Topical antibiotics (quinolones) vs boric acid Ear pain, discomfort, irritation · chronic suppurative otitis media Topical antibiotics (quinolones) may leads to lower ear pain, discomfort, irritation compared with boric acid (low certainty). Antibiotics versus topical antiseptics for chronic suppurative otitis media (2020) · Cochrane Headline outcomes only | RR 0.56 [0.32, 0.98] | 2 studies · 510 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Topical quinolone vs quinolones · people (of any age) with CSOM · 1 review
- Topical quinolone vs oral amoxicillin‐clavulanic acid combination · adults with CSOM · 1 review
- Topical quinolone vs intramuscular gentamicin · adults with CSOM · 1 review
- Topical quinolone vs povidone‐iodine · chronic suppurative otitis media · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.