Angiotensin‐converting enzyme inhibitors vs ARB: Cardiovascular events
- Population
- people with primary hypertension
- Intervention
- Angiotensin‐converting enzyme inhibitors
- Comparison
- ARB
- Outcome
- Cardiovascular events
All angiotensin converting enzyme (ACE) inhibitors showed no clear difference in total cardiovascular events compared with all angiotensin receptor blockers (ARBs) (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
All angiotensin converting enzyme (ACE) inhibitors vs all angiotensin receptor blockers (ARBs) Total cardiovascular events · people with primary hypertension All angiotensin converting enzyme (ACE) inhibitors showed no clear difference in total cardiovascular events compared with all angiotensin receptor blockers (ARBs) (low certainty). Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension (2014) · Cochrane Headline outcomes only | RR 1.07 [0.96, 1.19] | 3 studies · 5499 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension 2014 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Angiotensin‐converting enzyme inhibitors vs ARB · adults with early (stage 1 to 3) non‐diabetic CKD · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.