Question · asked by 1 review

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs: Rate of serious adverse events

Probiotics used as adjuvants to conventional antifungal drugs showed no clear difference in rate of serious adverse events compared with conventional antifungal drugs (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs
Rate of serious adverse events · non‐pregnant women with vulvovaginal candidiasis
Probiotics used as adjuvants to conventional antifungal drugs showed no clear difference in rate of serious adverse events compared with conventional antifungal drugs (low certainty).
Probiotics for vulvovaginal candidiasis in non‐pregnant women (2017) · Cochrane Headline outcomes only
RR 0.8 [0.22, 2.94]2 studies · 440 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Probiotics for vulvovaginal candidiasis in non‐pregnant women
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.