Question · asked by 1 review

Preoperative blood transfusion vs no transfusion: Perioperative complications ‐ any surgery‐related

Population
people with SCD
Intervention
Preoperative blood transfusion
Comparison
no transfusion
Outcome
Perioperative complications ‐ any surgery‐related

Preoperative blood transfusion showed no clear difference in perioperative complications ‐ any surgery‐related compared with no transfusion (low certainty).

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Preoperative blood transfusion vs no transfusion
Perioperative complications ‐ any surgery‐related · people with SCD
Preoperative blood transfusion showed no clear difference in perioperative complications ‐ any surgery‐related compared with no transfusion (low certainty).
Preoperative blood transfusions for sickle cell disease (2020) · Cochrane Headline outcomes only
RR 0.24 [0.03, 2.05]1 study · 65 participantsLow
Preoperative blood transfusion vs no transfusion
Perioperative complications ‐ any surgery‐related · people with SCD
Preoperative blood transfusion showed no clear difference in perioperative complications ‐ any surgery‐related compared with no transfusion (low certainty).
Preoperative blood transfusions for sickle cell disease (2016) · Cochrane Headline outcomes onlyearlier version CD003149.PUB3, superseded
RR 0.24 [0.03, 2.05]1 study · 65 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Preoperative blood transfusions for sickle cell disease
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.