Question · asked by 1 review
Pilocarpine vs placebo: Salivary flow rate
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Pilocarpine hydrochloride (parasympathomimetic) vs Placebo Salivary flow rates · Patients with radiation-induced salivary gland dysfunction Parasympathomimetic drugs for the treatment of salivary gland dysfunction due to radiotherapy (2015) · Cochrane All outcomes | Only two studies measured salivary flow rates (Johnson 1993; LeVeque 1993); no usable summary/pooled data reported. | 2 studies | GRADE not reported |
Pilocarpine hydrochloride (parasympathomimetic) vs Placebo Salivary flow rates · Patients with radiation-induced salivary gland dysfunction Parasympathomimetic drugs for the treatment of salivary gland dysfunction due to radiotherapy (2007) · Cochrane All outcomesearlier version CD003782.PUB2, superseded | Only two studies measured salivary flow rates (Johnson 1993; LeVeque 1993); no usable summary/pooled data reported. | 2 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Parasympathomimetic drugs for the treatment of salivary gland dysfunction due to radiotherapy 2015 · Cochrane All outcomes | 2015-07 | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.