IMMEDIATE initiation of cART vs DEFERRED initiation of cART: Death
- Population
- HIV‐positive, treatment‐naive children aged one to 12 years old
- Intervention
- IMMEDIATE initiation of cART
- Comparison
- DEFERRED initiation of cART
- Outcome
- Death
It is very uncertain whether IMMEDIATE initiation of cART changes death compared with DEFERRED initiation of cART (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
IMMEDIATE initiation of cART vs DEFERRED initiation of cART Death · HIV‐positive, treatment‐naive children aged one to 12 years old It is very uncertain whether IMMEDIATE initiation of cART changes death compared with DEFERRED initiation of cART (very low certainty). Optimal time for initiating antiretroviral therapy (ART) in HIV‐infected, treatment‐naive children aged 2 to… (2013) · Cochrane Headline outcomes only | RR 3 [0.12, 73.06] | 2 studies · 343 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Optimal time for initiating antiretroviral therapy (ART) in HIV‐infected, treatment‐naive children aged 2 to 5 years old 2013 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- IMMEDIATE initiation of cART vs DEFERRED initiation of cART · HIV‐positive, treatment‐naive children aged 24 to 59 months (2 to 5 years old) · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.