10 mg warfarin nomogram vs 5 mg warfarin nomogram: Major bleeding fall in hemoglobin of > 20 g/L or transfusion of 2 or more units of red cells
10 mg warfarin nomogram showed no clear difference in major bleeding fall in hemoglobin of > 20 g/L or transfusion of 2 or… compared with 5 mg warfarin nomogram (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
10 mg warfarin nomogram vs 5 mg warfarin nomogram Major bleeding fall in hemoglobin of > 20 g/L or transfusion of 2 or more units of red cells · patients with venous thromboembolism. 10 mg warfarin nomogram showed no clear difference in major bleeding fall in hemoglobin of > 20 g/L or transfusion of 2 or… compared with 5 mg warfarin nomogram (moderate certainty). Warfarin initiation nomograms for venous thromboembolism (2016) · Cochrane Headline outcomes only | RR 0.97 [0.27, 3.51] | 4 studies · 494 participants | Moderate |
10 mg warfarin nomogram vs 5 mg warfarin nomogram Major bleeding fall in hemoglobin of > 20 g/L or transfusion of 2 or more units of red cells · patients with venous thromboembolism. 10 mg warfarin nomogram showed no clear difference in major bleeding fall in hemoglobin of > 20 g/L or transfusion of 2 or… compared with 5 mg warfarin nomogram (moderate certainty). Warfarin initiation nomograms for venous thromboembolism (2013) · Cochrane Headline outcomes onlyearlier version CD007699.PUB2, superseded | RR 0.97 [0.27, 3.51] | 4 studies · 494 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Warfarin initiation nomograms for venous thromboembolism 2016 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.