Question · asked by 1 review

Probiotics vs placebo: Hypertensive disorders (including pre‐eclampsia, pregnancy‐induced hypertension, eclampsia)

Population
women with gestational diabetes mellitus
Intervention
Probiotics
Comparison
placebo
Outcome
Hypertensive disorders (including pre‐eclampsia, pregnancy‐induced hypertension, eclampsia)

Probiotic showed no clear difference in hypertensive disorders (including pre‐eclampsia, pregnancy‐induced… compared with placebo (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Probiotic vs placebo
Hypertensive disorders (including pre‐eclampsia, pregnancy‐induced hypertension, eclampsia) · pregnant women diagnosed with gestational diabetes
Probiotic showed no clear difference in hypertensive disorders (including pre‐eclampsia, pregnancy‐induced… compared with placebo (low certainty).
Probiotic treatment for women with gestational diabetes to improve maternal and infant health and well‐being (2020) · Cochrane Headline outcomes only
RR 1.5 [0.64, 3.53]3 studies · 256 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Probiotic treatment for women with gestational diabetes to improve maternal and infant health and well‐being
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.